Research Scientist, RNAi Discovery

Duration: 12-month contract

Location: Onsite in Lexington, MA

Key Responsibilities

• siRNA drug candidate screening, hit identification, and lead optimization
• Cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening (e.g., transfection); cell-based assays ; PCR
• In vivo drug candidate testing (e.g., mouse dosing; sample analysis)
• Innovate and advance research projects aimed at further optimizing the GalXCTM platform
• Produce high-quality technical reports and summaries for internal use and for inclusion in key regulatory documents

Qualifications

• PhD in cell or molecular biology or a related field, ideally with 1-2 years post-degree experience preferably in drug discovery and in an industry setting
• Expertise in cellular and molecular biology is essential (e.g., mammalian cell culture; cell-based assays; quantitative real-time PCR)
• Experience with siRNA/microRNA biology is desired
• Proficiency in animal handling, dosing, and necropsy is desired
• Ability to perform and interpret experiments rigorously and reliably, and to advance projects aggressively towards defined goals is expected

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