The Moores Cancer Center is one of just 53 NCI-designated Comprehensive Cancer Centers in the United States and the only one in San Diego County. As a consortium cancer center, it is a collaborative partnership between the UCSD: encompassing 14 departments (12 clinical, 2 basic sciences), 3 professional schools (School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, School of Public Health), UCSD Health oncology hospitals and clinics; the basic and public health research and outreach of San Diego State University, and the basic and translational research of the La Jolla Institute of Immunology. These various programs and units are all dedicated to fulfilling the Moores Cancer Center's mission of reducing cancer's burden. As such, it ranks among the top centers in the nation conducting the continuum of cancer research, providing advanced patient care, and serving the community through outreach and education programs. As a top-ranking, future-oriented organization, we offer challenging career opportunities in a fast-paced and innovative environment. Moores Cancer Center follows a progressive philosophy of career-path development for its employees including opportunities for cross-training, professional development, and progressive responsibility.

MCC's mission is to transform cancer care in our catchment area and beyond by driving exceptional scientific discoveries, and innovations in prevention, detection, care, and training. MCC will make a global impact on improving health by reducing cancer burden through accelerated discovery and translation, compassionate and interdisciplinary care, education and community engagement, with the foundation of our core values - Excellence, Innovation and Risk-Taking, Collaboration, Diversity and Service.

Under supervision in a hematology/oncology research lab, assist with performing research studies and troubleshooting new and established assay techniques. Assist with performing and analyzing in vivo and in vitro experiments to study expression of specific proteins in ovarian, breast, and lung cancer and to define the role of specific proteins in promoting tumor growth, metastasis, and tumor initiation using primary cancer cells and cell lines. Assist with conducting in vivo experiments with patient-derived xenograft mouse models to assess treatment effects with novel agents. Assist with processing and banking primary human and mouse tumor samples. Other duties assigned as needed.

MINIMUM QUALIFICATIONS

• Theoretical knowledge of immunology, molecular biology, cell biology, and protein chemistry.

• Ability to perform standard molecular biology techniques, including PCR, SDS Page electrophoresis, western blotting, ELISA assays, and recombinant DNA manipulation.

• Ability to culture primary tumor cells. Knowledge of various mice handling techniques. Ability to assist with performing tumor isolation from mice, tumor freezing and formalin-fixing procedures.

• Knowledge and willingness to handle blood, plasma and other human specimens for processing and shipping. Must be willing and able to work with human samples, animals, biohazardous materials and radioactivity.

• Excellent organizational skills to order and maintain lab equipment and order supplies. Ability to maintain confidentiality.

• Ability to follow UCSD Safety and Hazardous Materials guidelines. Ability and willingness to work with hazardous/biohazardous materials.

• Knowledge of various cell based assays pertaining to investigating cancer stem cell hypothesis.

• Excellent interpersonal and oral communication skills. Demonstrated skill to effectively and clearly communicate with tact, diplomacy, discretion, and flexibility to faculty, academicians, students, and staff including those of diverse ethnicity, culture, and foreign nationals. Ability to present information clearly and concisely.

PREFERRED QUALIFICATIONS

• Knowledge of the cancer stem cell hypothesis and markers, particularly as it pertains to ovarian cancer, breast cancer, and lung cancer.

• Ability to establish patient-derived xenograft (PDX) including subcutaneous injection model and orthotopic mice model.

• Experience working with solid tumors, including breast and ovarian cancer.

• Experience in mice orbital bleeding for various studies relating to anti-cancer drugs.

• Knowledge and experience in flow cytometry and operation of a FACS Celesta instrument. Ability to assist with performing and interpreting results from experiments with human and mouse cells stained with specific fluorochrome-conjugated monoclonal antibodies.

SPECIAL CONDITIONS

• Employment is subject to a criminal background check.

• Must be able to maintain confidentiality.

• Must be willing and able to work holidays, weekends and evenings when necessary.

• Must be able to handle blood samples and be trained for biohazards.

Pay Transparency ActFull Salary Range: $51,949 - $61,972 Annually

The University of California, San Diego is required to provide a reasonable estimate of the compensation range for this role. This range takes into account the wide range of factors that are considered in making compensation decisions including but not limited to experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be offered a salary at or near the top of the range for a position. Salary offers are determined based on final candidate qualifications and experience. The full salary range for this position is defined as the Full Pay Range. The budgeted salary or hourly range that the University reasonably expects to pay for this position defined as the Expected Pay Scale. Placement within the Expected Pay Scale is determined by internal equity, relevant qualifications, and collective bargaining agreements (when applicable).

Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral).

If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.

UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!

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