We are currently searching forBioinformatics Scientisttoprovidebioinformatics support to advance the institute research programs, with a primary focus on single cell and spatial omics data analysis. This is a full-time, on-site opportunity inDurham, NC.

• Collaborate with scientists to design, analyze,manageand interpret all types of data.
• Conduct analyses on NextGen sequencing data including data derived inChIP-Seq,RNA-Seq, miRNA-Seq and other experimental models.
• Work with an interdisciplinary team to apply computational data analysis approaches to make biological discoveries.
• Conduct analysis and interpretationondata from genomic platforms including expression, exon, tiling,promoterandothersarray types.
• Work independently with research groups to develop, implement, and refine analyticalpipelinefor single cell data analysis.
• Develop,optimize, andmaintainbioinformatics pipelines, scripts, and computational tools for large-scale data analysis (e.g., NGS,scRNA-seq, multi-omics).
• Perform advanced statistical and computational analyses to interpret complex datasets and derive actionable biological insights.
• Collaborate with scientists and researchers to design experiments, selectappropriate analyticalapproaches, and troubleshoot methodologies.
• Integrate and analyze diverse genomic and multi-omicdatasets, including sequencing and public data sources.
• Install, configure, and support scientific software across computing platforms; ensure reproducibility through standardized workflows and documentation.
• Generate reports, visualizations, and presentations to communicate findings to scientific and technical audiences.
• Evaluate and implement new bioinformatics tools, statistical methods, and computational approaches based on current literature and research needs.
• Provide training and technical guidance to staff on bioinformatics tools, pipelines, and data analysis techniques.
• Maintain detailed documentation, laboratory records, and progress reports; present findings at meetings and contribute to publications.
• Support interdisciplinary collaborations and contribute to advancing researchobjectivesaligned with organizationalmission.
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• Must be able to obtain and maintain a Federal or DoD “public trust”; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.

What You Will Need:

• Master’s degree in bioinformatics,biostatistics,computationalbiologyor biological/life science.
• At leastTWO (2)years ofdata analysisexperience.
• Advancedproficiencyindisciplinessuch asstatistical modeling, machine learning, and integrative analysis to extract biologically meaningfulinsights from complex cellular systems.
• Knowledgeable with avariety of next gen sequencing techniques.
• Experience working withanalyticaltools,softwareand platforms such as, but not limited to, R, Python, MATLAB, SAS, PERL, Java, Shell, Bash, Seurat /Scanpy,Linux,Unix,Bioconductor,Cloud computing,High-PerformanceComputing (HPC).
• Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must obtain approved adjudication of their public trust prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred

What Would Be Nice To Have:

• PhD preferred
• Strong verbal and writtencommunication skills
• Familiar with multiplenext gen sequencingtechniques
• Ability to collaborate closely with investigators and multidisciplinary teams to design analytical strategies, ensure data quality, interpret results, and translate findings into actionable scientific conclusions.

What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

• Medical, Rx, Dental & Vision Insurance
• Personal and Family Sick Time & Company Paid Holidays
• Parental Leave
• 401(k) Retirement Plan
• Group Term Life and Travel Assistance
• Voluntary Life and AD&D Insurance
• Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
• Transit and Parking Commuter Benefits
• Short-Term & Long-Term Disability
• Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
• Employee Referral Program
• Corporate Sponsored Events & Community Outreach
• Care.com annual membership
• Employee Assistance Program
• Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
• Position may be eligible for a discretionary variable incentive bonus

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