We are currently searching forBioinformatics Scientisttoprovidebioinformatics support to advance the institute research programs, with a primary focus on single cell and spatial omics data analysis. This is a full-time, on-site opportunity inDurham, NC.
- Collaborate with scientists to design, analyze,manageand interpret all types of data.
- Conduct analyses on NextGen sequencing data including data derived inChIP-Seq,RNA-Seq, miRNA-Seq and other experimental models.
- Work with an interdisciplinary team to apply computational data analysis approaches to make biological discoveries.
- Conduct analysis and interpretationondata from genomic platforms including expression, exon, tiling,promoterandothersarray types.
- Work independently with research groups to develop, implement, and refine analyticalpipelinefor single cell data analysis.
- Develop,optimize, andmaintainbioinformatics pipelines, scripts, and computational tools for large-scale data analysis (e.g., NGS,scRNA-seq, multi-omics).
- Perform advanced statistical and computational analyses to interpret complex datasets and derive actionable biological insights.
- Collaborate with scientists and researchers to design experiments, selectappropriate analyticalapproaches, and troubleshoot methodologies.
- Integrate and analyze diverse genomic and multi-omicdatasets, including sequencing and public data sources.
- Install, configure, and support scientific software across computing platforms; ensure reproducibility through standardized workflows and documentation.
- Generate reports, visualizations, and presentations to communicate findings to scientific and technical audiences.
- Evaluate and implement new bioinformatics tools, statistical methods, and computational approaches based on current literature and research needs.
- Provide training and technical guidance to staff on bioinformatics tools, pipelines, and data analysis techniques.
- Maintain detailed documentation, laboratory records, and progress reports; present findings at meetings and contribute to publications.
- Support interdisciplinary collaborations and contribute to advancing researchobjectivesaligned with organizationalmission.
- Must be able to obtain and maintain a Federal or DoD “public trust”; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.
What You Will Need:
- Master’s degree in bioinformatics,biostatistics,computationalbiologyor biological/life science.
- At leastTWO (2)years ofdata analysisexperience.
- Advancedproficiencyindisciplinessuch asstatistical modeling, machine learning, and integrative analysis to extract biologically meaningfulinsights from complex cellular systems.
- Knowledgeable with avariety of next gen sequencing techniques.
- Experience working withanalyticaltools,softwareand platforms such as, but not limited to, R, Python, MATLAB, SAS, PERL, Java, Shell, Bash, Seurat /Scanpy,Linux,Unix,Bioconductor,Cloud computing,High-PerformanceComputing (HPC).
- Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must obtain approved adjudication of their public trust prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred
What Would Be Nice To Have:
- PhD preferred
- Strong verbal and writtencommunication skills
- Familiar with multiplenext gen sequencingtechniques
- Ability to collaborate closely with investigators and multidisciplinary teams to design analytical strategies, ensure data quality, interpret results, and translate findings into actionable scientific conclusions.
What We Offer:
Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
- Medical, Rx, Dental & Vision Insurance
- Personal and Family Sick Time & Company Paid Holidays
- Parental Leave
- 401(k) Retirement Plan
- Group Term Life and Travel Assistance
- Voluntary Life and AD&D Insurance
- Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
- Transit and Parking Commuter Benefits
- Short-Term & Long-Term Disability
- Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
- Employee Referral Program
- Corporate Sponsored Events & Community Outreach
- Care.com annual membership
- Employee Assistance Program
- Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
- Position may be eligible for a discretionary variable incentive bonus
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